|
Symbol Name ID |
Isl1
ISL1 transcription factor, LIM/homeodomain MGI:101791 |
| Darker colors indicate more annotations |
| Human Phenotypes | Unroofed coronary sinus |
Atrial septal defect |
Primum atrial septal defect |
Secundum atrial septal defect |
Sinus venosus atrial septal defect |
Ventricular septal defect |
Perimembranous ventricular septal defect |
Atrioventricular canal defect |
Complete atrioventricular canal defect |
Right ventricular dilatation |
Double outlet right ventricle |
Tetralogy of Fallot |
Transposition of the great arteries |
Cardiomegaly |
Hypoplastic left heart |
Coarctation of aorta |
Pulmonary artery atresia |
Pulmonary artery stenosis |
Patent ductus arteriosus |
Truncus arteriosus |
Stroke |
Heart murmur |
Systolic heart murmur |
Pulmonic stenosis |
Pulmonary arterial hypertension |
Right axis deviation |
Palpitations |
Atrial fibrillation |
Atrial flutter |
Tachycardia |
Right bundle branch block |
Congestive heart failure |
Aplasia/Hypoplasia of the thymus |
| Disease(s) Associated with ISL1 | |||||||||||||||||||||||||||||||||
| atrial heart septal defect | |||||||||||||||||||||||||||||||||
| double outlet right ventricle | |||||||||||||||||||||||||||||||||
| ventricular septal defect |
| Mouse Phenotypes | abnormal dorsal aorta morphology |
abnormal vascular endothelial cell morphology |
absent cardiac outflow tract |
abnormal heart development |
failure of heart looping |
abnormal heart atrium morphology |
abnormal heart shape |
absent heart right ventricle |
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| Availability | Mouse Genotype | ||||||||
| Isl1tm1Tmj/Isl1tm1Tmj | |||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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